Details of the Drug

General Information of Drug (ID: DM9C8FP)

• Drug Name: I-BRD9
• Synonyms: GSK602; compound 45 [PMID 25856009]

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

• Drug Type: Small molecular drug
• #Ro5 Violations (Lipinski): 0:
  Molecular Weight (mw); 497.6
  Logarithm of the Partition Coefficient (xlogp); 2.9
  Rotatable Bond Count (rotbonds); 4
  Hydrogen Bond Donor Count (hbonddonor); 1
  Hydrogen Bond Acceptor Count (hbondacc); 8
• Chemical Identifiers:
  Formula: C22H22F3N3O3S2
  IUPAC Name: N'-(1,1-dioxothian-4-yl)-5-ethyl-4-oxo-7-[3-(trifluoromethyl)phenyl]thieno[3,2-c]pyridine-2-carboximidamide
  Canonical SMILES: CCN1C=C(C2=C(C1=O)C=C(S2)C(=NC3CCS(=O)(=O)CC3)N)C4=CC(=CC=C4)C(F)(F)F
  InChI: InChI=1S/C22H22F3N3O3S2/c1-2-28-12-17(13-4-3-5-14(10-13)22(23,24)25)19-16(21(28)29)11-18(32-19)20(26)27-15-6-8-33(30,31)9-7-15/h3-5,10-12,15H,2,6-9H2,1H3,(H2,26,27)
  InChIKey: WRUWGLUCNBMGPS-UHFFFAOYSA-N
• Cross-matching ID:
  PubChem CID: 91668541
  TTD ID: D0N5BI

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Bromodomain-containing protein 9 (BRD9)	TTR7L5Y	BRD9_HUMAN	Inhibitor	[1]

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Bone Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
RPMI-3460/CS1	GDSC2	4.7214	7.8726	2.0802	4.5977
CHSA0011	GDSC2	3.4729	6.4948	1.8595	8.8207
HuO9	GDSC2	3.5002	5.9242	2.1662	6.8141
EW-12	GDSC2	3.6534	6.5405	1.9798	7.5763
SJSA-1	GDSC2	3.6544	6.6375	1.9324	7.8704
CAL-72	GDSC2	3.7292	9.3618	0.6344	15.4226
ES8	GDSC2	3.8264	5.7627	2.4922	3.9555
NOS-1 [Human HNSCC]	GDSC2	3.8362	6.72	2.0301	6.7957
EW-18	GDSC2	3.8779	6.2656	2.2838	5.1217
SK-PN-DW	GDSC2	3.9127	9.1049	0.9069	13.3865
EW-1	GDSC2	3.9476	6.3566	2.2891	4.9284
CHSA0108	GDSC2	4.1769	6.4346	2.4074	3.725
A-673	GDSC2	4.2003	6.2055	2.5299	2.9625
HuO-3N1	GDSC2	4.2106	8.0169	1.6675	8.1234
EW-22	GDSC2	4.2234	8.9763	1.2063	10.8491
ES1	GDSC2	4.3113	7.4489	2.0134	5.8047
HOS	GDSC2	4.3161	8.4872	1.5136	8.803
EW-7	GDSC2	4.3433	11.269	0.1642	16.2585
MG-63	GDSC2	4.3489	8.6343	1.4653	9.0146
EW-16	GDSC2	4.38	6.994	2.275	4.1083
CAL-78	GDSC2	4.4029	6.6472	2.4505	3.0532
EW-3	GDSC2	4.4669	6.8869	2.3792	3.346
ES5	GDSC2	4.4728	10.3231	0.7281	12.957
G-292 clone A141B1	GDSC2	4.6369	8.4006	1.7772	6.5296
ES7	GDSC2	4.6428	7.4547	2.2251	3.9114
EW-24	GDSC2	4.7227	6.2614	2.7907	0.8916
TC-71	GDSC2	4.7532	6.4591	2.7247	1.1446
CHSA8926	GDSC2	4.76	7.8612	2.1094	4.3611
MHH-ES-1	GDSC2	4.8015	6.6677	2.6619	1.3758
SK-ES-1	GDSC2	4.8038	7.0255	2.5106	2.1083
U2OS	GDSC2	4.9349	8.0075	2.1478	3.8451
H-EMC-SS	GDSC2	4.9638	8.3206	2.0222	4.4955
EW-11	GDSC2	5.0655	11.3107	0.6707	11.8835
NY	GDSC2	5.0934	11.0525	0.8148	11.0457
ES6	GDSC2	5.1509	13.9794	-0.5701	17.7205
CADO-ES1	GDSC2	5.2169	7.0873	2.6871	0.8758
U-CH2	GDSC2	5.2477	7.3771	2.5859	1.2493
EW-13	GDSC2	5.3581	7.4551	2.6055	1.0718
SaOS-2	GDSC2	5.5001	12.372	0.4583	12.0513
ES4	GDSC2	6.4308	8.5401	2.6379	0.3707

Cancer Drug Sensitivity Data Curated from 162 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
JM1	GDSC2	3.8694	5.8543	2.4779	3.9467
Jurkat	GDSC2	1.1505	3.9632	0.7505	23.9245
SUP-B8	GDSC2	1.277	4.3952	0.7269	23.4935
NCI-H929	GDSC2	1.5006	5.0981	0.6733	22.8339
Kasumi-1	GDSC2	1.6454	3.3499	1.4845	17.6731
OCI-AML-3	GDSC2	1.6983	3.7965	1.4009	17.8996
JVM-3	GDSC2	1.7625	11.2784	-2.0205	32.819
SR	GDSC2	1.854	4.3021	1.3761	17.3784
MV4-11	GDSC2	1.887	12.563	-2.5429	33.7545
L-1236	GDSC2	1.9668	4.0064	1.6127	15.5434
Mono-Mac-6	GDSC2	1.9998	5.2957	1.0946	18.4376
THP-1	GDSC2	2.0444	4.5115	1.4882	15.9483
MOLM-16	GDSC2	2.0516	3.7268	1.8072	14.0719
SU-DHL-5	GDSC2	2.0656	3.151	1.9935	12.9822
KMS-12-BM	GDSC2	2.1225	3.585	1.9328	13.0559
CRO-AP2	GDSC2	2.1357	4.2552	1.6916	14.3852
MHH-CALL-4	GDSC2	2.1546	4.7405	1.5016	15.433
LC4-1	GDSC2	2.1565	5.1664	1.3107	16.5619
BC-1	GDSC2	2.2484	5.1339	1.4172	15.578
BONNA-12	GDSC2	2.3078	4.9097	1.5797	14.3769
RPMI-8402	GDSC2	2.3605	4.2395	1.9324	12.0622
DEL	GDSC2	2.394	5.9266	1.1837	16.4431
WSU-DLCL2	GDSC2	2.397	4.7206	1.7556	12.9783
Karpas-422	GDSC2	2.4413	10.7255	-1.1371	27.6457
NB4	GDSC2	2.487	3.7267	2.2753	9.5399
WSU-NHL	GDSC2	2.5025	4.8949	1.7796	12.439
SUP-T1	GDSC2	2.5106	5.3359	1.5787	13.6364
BC-3	GDSC2	2.5457	4.1391	2.167	9.935
Jiyoye	GDSC2	2.5789	4.4801	2.0478	10.5239
Karpas-45	GDSC2	2.6067	3.7893	2.378	8.4461
SU-DHL-16	GDSC2	2.6484	4.1044	2.2876	8.8127
KMS-11	GDSC2	2.7221	5.3819	1.7575	11.7938
KY821	GDSC2	2.7252	6.1071	1.4054	13.9536
AMO1	GDSC2	2.7334	4.6169	2.1364	9.4127
JSC-1	GDSC2	2.8215	4.2393	2.4002	7.4749
RCH-ACV	GDSC2	2.8259	4.4766	2.2927	8.1185
SKM-1	GDSC2	2.837	5.378	1.8662	10.7275
MOLT-13	GDSC2	2.8502	6.1669	1.4894	13.0226
EoL-1	GDSC2	2.8614	7.1278	1.0228	15.8085
KE-37	GDSC2	2.8676	5.7907	1.6911	11.7168
Namalwa	GDSC2	2.887	4.4143	2.3814	7.353
HT	GDSC2	2.8885	12.8967	-1.8312	28.592
SU-DHL-10	GDSC2	2.8908	3.6713	2.7251	5.254
MOLM-13	GDSC2	2.8955	4.1704	2.5053	6.5601
JJN-3	GDSC2	2.8974	6.4244	1.4041	13.3939
SK-MM-2	GDSC2	2.9087	4.8752	2.1788	8.536
TALL-1 [Human adult T-ALL]	GDSC2	2.9285	4.2547	2.4976	6.4884
OPM-2	GDSC2	2.9304	4.5844	2.3407	7.4535
OCI-Ly7	GDSC2	2.9762	4.1471	2.5949	5.718
LAMA-84	GDSC2	2.9794	4.2349	2.556	5.9467
ST486	GDSC2	2.999	4.3348	2.5264	6.0615
BE-13	GDSC2	3.0029	5.4267	1.9931	9.3875
ML-2	GDSC2	3.012	4.9765	2.224	7.9077
697	GDSC2	3.0357	4.5233	2.4687	6.2961
CTV-1	GDSC2	3.0408	4.6832	2.3949	6.7414
JVM-2	GDSC2	3.0593	5.9146	1.8008	10.4154
Farage	GDSC2	3.0633	4.2098	2.6475	5.0864
A3/Kawakami	GDSC2	3.071	3.9634	2.7738	4.2761
OCI-M1	GDSC2	3.077	3.9761	2.7735	4.257
BALL-1	GDSC2	3.0896	5.8427	1.863	9.9301
H9	GDSC2	3.0925	4.7367	2.4153	6.4442
GR-ST	GDSC2	3.1081	5.2611	2.1688	7.947
DB	GDSC2	3.115	5.0305	2.2896	7.1638
GDM-1	GDSC2	3.1373	4.9104	2.369	6.5923
ALL-PO	GDSC2	3.1386	5.6506	2.0015	8.9069
A4/Fukuda	GDSC2	3.1539	4.1997	2.7362	4.2277
DG-75	GDSC2	3.1556	4.9719	2.3545	6.6268
RL	GDSC2	3.1691	4.8463	2.4289	6.1144
Ku812	GDSC2	3.179	4.5397	2.5902	5.0663
HEL	GDSC2	3.2004	4.9615	2.3987	6.2085
NALM-6	GDSC2	3.2199	5.1971	2.298	6.7852
IM-9	GDSC2	3.2521	4.8567	2.4956	5.4383
SU-DHL-1	GDSC2	3.2578	7.3062	1.2761	13.0548
WIL2 NS	GDSC2	3.2726	4.6702	2.6063	4.6764
U-698-M	GDSC2	3.2768	4.506	2.6918	4.1226
P30/OHK	GDSC2	3.2848	4.4077	2.7477	3.745
OCI-AML-2	GDSC2	3.285	4.4006	2.7515	3.7202
NKM-1	GDSC2	3.2957	5.0066	2.4577	5.5485
Loucy	GDSC2	3.3215	5.1032	2.4309	5.6427
MLMA	GDSC2	3.3255	5.4029	2.2844	6.558
CTB-1	GDSC2	3.3404	4.896	2.5502	4.8324
PF-382	GDSC2	3.3651	5.4264	2.3055	6.311
GA-10	GDSC2	3.3845	5.1366	2.4662	5.2389
CCRF-CEM	GDSC2	3.3896	5.9765	2.0506	7.8526
KOPN-8	GDSC2	3.4008	4.7188	2.6881	3.7899
Karpas-299	GDSC2	3.4329	5.0325	2.5573	4.528
MOLP-8	GDSC2	3.4414	5.2779	2.4416	5.236
SU-DHL-6	GDSC2	3.4418	4.9699	2.5956	4.2615
NU-DUL-1	GDSC2	3.4447	4.7811	2.692	3.6454
HL-60	GDSC2	3.4586	5.2537	2.4675	5.0252
Karpas-1106P	GDSC2	3.4603	6.4132	1.89	8.6644
NOMO-1	GDSC2	3.4645	5.1413	2.5281	4.6266
MHH-CALL-2	GDSC2	3.4813	5.7163	2.2548	6.3067
MN-60	GDSC2	3.4877	5.4454	2.395	5.4044
BV-173	GDSC2	3.4973	5.0942	2.5774	4.2283
JeKo-1	GDSC2	3.5226	5.1028	2.5927	4.0657
RPMI-8226	GDSC2	3.5417	5.1417	2.588	4.0456
YT	GDSC2	3.5464	4.9369	2.693	3.3753
ARH-77	GDSC2	3.5642	5.2874	2.5331	4.3327
RC-K8	GDSC2	3.5724	5.1466	2.609	3.836
RPMI-6666	GDSC2	3.5839	5.3636	2.5103	4.4258
L-540	GDSC2	3.5874	5.7394	2.3266	5.5706
Raji	GDSC2	3.5875	5.073	2.6567	3.5002
ATN-1	GDSC2	3.5935	5.0124	2.6909	3.2714
VAL	GDSC2	3.595	5.2804	2.5599	4.0868
MY-M12	GDSC2	3.6157	6.4424	1.9992	7.5545
MEG-01	GDSC2	3.6249	5.6361	2.4067	4.9714
EB2	GDSC2	3.6274	5.2888	2.58	3.8805
CML-T1	GDSC2	3.6734	5.0336	2.7384	2.7892
L-363	GDSC2	3.686	5.9384	2.3033	5.4647
Karpas-620	GDSC2	3.699	7.7451	1.4162	10.9465
Ramos.2G6.4C10	GDSC2	3.7137	8.4638	1.0697	12.9815
MC116	GDSC2	3.7587	5.1822	2.7258	2.6773
P31/FUJ	GDSC2	3.7731	6.0255	2.3252	5.1136
Reh	GDSC2	3.7781	6.5564	2.0674	6.7083
ROS-50	GDSC2	3.783	5.6778	2.5027	3.9903
MOLT-16	GDSC2	3.7867	5.3523	2.6631	2.9982
CESS	GDSC2	3.8089	5.7424	2.4896	4.0113
P32/ISH	GDSC2	3.8111	5.3763	2.6683	2.9138
BL-41	GDSC2	3.8238	5.708	2.5169	3.8098
HH [Human lymphoma]	GDSC2	3.8567	6.318	2.2429	5.4246
SU-DHL-4	GDSC2	3.8681	5.6253	2.5875	3.2817
MM1.S	GDSC2	3.8691	6.6415	2.0931	6.3236
ME1	GDSC2	3.8931	5.5208	2.6543	2.8261
Daudi	GDSC2	3.9283	5.9777	2.4591	3.9313
P12-Ichikawa	GDSC2	3.9338	5.707	2.5927	3.1117
CA46	GDSC2	3.9844	6.6667	2.1644	5.6107
DND-41	GDSC2	4.0057	7.1924	1.9228	7.0485
KMOE-2	GDSC2	4.0221	5.8074	2.603	2.8732
SUP-B15	GDSC2	4.0867	6.1591	2.4788	3.481
LP-1	GDSC2	4.159	6.1151	2.5461	2.9453
EM-2	GDSC2	4.1655	6.4476	2.3939	3.828
U266B1	GDSC2	4.1671	7.0997	2.0826	5.6995
MHH-PREB-1	GDSC2	4.1821	5.8628	2.6766	2.1588
HC-1	GDSC2	4.192	6.2358	2.5105	3.0901
VL51	GDSC2	4.2385	6.3128	2.5038	3.0427
OCI-Ly19	GDSC2	4.2553	6.4579	2.4468	3.3422
QIMR-WIL	GDSC2	4.323	6.8146	2.3228	3.9382
PL-21	GDSC2	4.3707	8.0053	1.7862	7.0427
ALL-SIL	GDSC2	4.3719	7.754	1.9081	6.3081
KG-1	GDSC2	4.3741	6.3848	2.5531	2.5263
MOLT-4	GDSC2	4.3903	6.7951	2.3745	3.5108
K-562	GDSC2	4.4433	6.2392	2.6578	1.8537
SCC-3	GDSC2	4.4535	5.6955	2.8931	0.7189
KM-H2	GDSC2	4.4559	8.3044	1.7007	7.3675
EJM	GDSC2	4.4573	6.9673	2.3361	3.6095
NK-92MI	GDSC2	4.602	6.4778	2.6398	1.7265
SUP-M2	GDSC2	4.6181	6.0113	2.8426	0.7747
KCL-22	GDSC2	4.7408	7.0184	2.4793	2.3576
Karpas-231	GDSC2	4.8039	6.0664	2.9023	0.4215
TUR	GDSC2	4.9766	6.7006	2.7318	0.902
SIG-M5	GDSC2	5.0288	6.0297	3.0008	0.1066
TK [Human B-cell lymphoma]	GDSC2	5.2324	6.7685	2.815	0.4421
RS4;11	GDSC2	5.2445	7.153	2.6736	0.9043
L-428	GDSC2	5.2986	6.717	2.8595	0.2963
HAL-01	GDSC2	5.3619	7.3843	2.6351	0.9558
SU-DHL-8	GDSC2	5.363	7.007	2.7793	0.4753
DoHH2	GDSC2	5.4748	6.8247	2.8869	0.1827
Hs 445	GDSC2	5.5298	7.0916	2.8135	0.3125
Granta-519	GDSC2	6.0103	7.9829	2.6774	0.4401
HDLM-2	GDSC2	6.0336	8.3951	2.5347	0.8322
SUP-HD1	GDSC2	6.1768	8.2348	2.6507	0.4359

Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SK-GT-4	GDSC2	3.944	6.8273	2.0567	6.3691
HCE-4	GDSC2	4.3972	8.5838	1.5243	8.5515
FLO-1	GDSC2	4.4277	9.9297	0.8882	12.177
OACM5.1 C	GDSC2	4.4806	11.0349	0.3833	14.7864
TE-12	GDSC2	4.4975	7.8861	1.9296	5.9153
KYAE-1	GDSC2	4.6906	6.7307	2.5777	1.9211
KYSE-50	GDSC2	4.8103	7.0133	2.5193	2.055
KYSE-220	GDSC2	4.906	7.0925	2.5357	1.85
OACP4 C	GDSC2	5.5704	8.389	2.3262	2.0563
ESO-26	GDSC2	5.9714	7.6973	2.7641	0.2657
ESO-51	GDSC2	6.2109	8.0856	2.7162	0.2849

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
COLO 684	GDSC2	4.0758	8.0165	1.5695	9.0414

Cancer Drug Sensitivity Data Curated from 32 Cell Line(s) in Autonomic Ganglia Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
NB69	GDSC2	3.2082	5.8977	1.9381	9.0942
KP-N-YS	GDSC2	3.7307	5.8336	2.3883	4.8233
SJNB-13	GDSC2	3.7501	5.7865	2.4257	4.5439
LA-N-6	GDSC2	4.0265	8.4648	1.3115	10.7191
SJNB-14	GDSC2	4.0432	7.1366	1.9772	6.6252
KP-N-YN	GDSC2	4.118	9.8809	0.6799	14.1202
SK-N-FI	GDSC2	4.1555	6.9059	2.1681	5.2061
SJNB-10	GDSC2	4.2619	10.8642	0.3026	15.7625
CHP-134	GDSC2	4.2726	6.6	2.3913	3.6335
MHH-NB-11	GDSC2	4.2736	7.6339	1.8983	6.582
NB(TU)1	GDSC2	4.2977	7.4392	2.0088	5.862
IMR-5	GDSC2	4.3558	7.167	2.1777	4.7302
SK-N-MC-IXC	GDSC2	4.38	11.1623	0.2449	15.7553
GOTO	GDSC2	4.3881	7.0199	2.268	4.1341
KP-N-RT-BM-1	GDSC2	4.4243	7.4904	2.0693	5.2353
CHP-212	GDSC2	4.4712	6.0239	2.7658	1.273
SK-N-AS	GDSC2	4.4756	7.277	2.2033	4.3446
GI-ME-N	GDSC2	4.5325	8.1907	1.8075	6.567
TGW	GDSC2	4.5758	8.391	1.7409	6.8709
SiMa	GDSC2	4.7817	10.1356	1.0416	10.4815
SJNB-7	GDSC2	4.8865	9.0855	1.6165	6.9604
SJNB-5	GDSC2	4.9891	11.5133	0.5188	12.8607
CHP-126	GDSC2	4.9908	7.2894	2.4958	1.9387
SJNB-6	GDSC2	5.2121	6.9733	2.7293	0.7272
Kelly	GDSC2	5.216	7.041	2.7048	0.8114
SK-N-DZ	GDSC2	5.3948	6.827	2.8567	0.2664
SK-N-BE(2)-M17	GDSC2	5.4751	7.1846	2.7586	0.4756
SK-N-SH	GDSC2	5.5639	7.3277	2.7413	0.4788
SJNB-17	GDSC2	5.5794	7.5258	2.6739	0.6694
NH-12	GDSC2	5.6272	7.7891	2.5938	0.9054
NB1	GDSC2	5.7412	7.6233	2.7031	0.4956
SJNB-12	GDSC2	5.9227	7.9614	2.6511	0.548

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Biliary Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HuCC-T1	GDSC2	4.2934	8.2121	1.6315	8.1482

Cancer Drug Sensitivity Data Curated from 51 Cell Line(s) in Breast Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HCC2157	GDSC2	3.1171	9.7004	-0.0395	20.7507
COLO 824	GDSC2	3.6557	6.6876	1.9085	8.0165
HCC1599	GDSC2	3.7725	5.687	2.4906	4.0891
Evsa-T	GDSC2	3.8025	5.8702	2.4227	4.4389
HCC1569	GDSC2	3.8989	10.4217	0.2406	17.0523
MDA-MB-330	GDSC2	3.9463	8.5067	1.2297	11.4125
YMB-1-E	GDSC2	3.9943	6.2168	2.3893	4.2127
CAMA-1	GDSC2	4.0115	6.9696	2.0359	6.3382
MDA-MB-157	GDSC2	4.0786	8.7115	1.2288	11.0778
MDA-MB-453	GDSC2	4.1011	7.94	1.6257	8.6383
Hs 578T	GDSC2	4.1171	7.7406	1.7352	7.933
AU565	GDSC2	4.1244	7.7081	1.7564	7.7864
DU4475	GDSC2	4.1471	6.426	2.392	3.8765
CAL-120	GDSC2	4.148	6.6651	2.2785	4.5545
HDQ-P1	GDSC2	4.1813	7.3837	1.955	6.4442
OCUB-M	GDSC2	4.2126	7.085	2.121	5.368
MDA-MB-361	GDSC2	4.213	6.0391	2.6146	2.4548
HCC70	GDSC2	4.2279	7.3972	1.981	6.1819
HCC1428	GDSC2	4.2986	10.9104	0.3077	15.6411
MDA-MB-175-VII	GDSC2	4.3595	6.0749	2.6838	1.8398
MDA-MB-415	GDSC2	4.3662	8.5677	1.5102	8.7069
BT-474	GDSC2	4.3829	6.0442	2.7102	1.6676
ZR-75-30	GDSC2	4.4568	8.4301	1.6406	7.7244
BT-549	GDSC2	4.4623	9.4979	1.1251	10.7436
HCC1395	GDSC2	4.4946	6.5607	2.5439	2.3833
CAL-51	GDSC2	4.5144	6.9952	2.3583	3.381
MRK-nu-1	GDSC2	4.5442	7.1068	2.3251	3.517
MDA-MB-231	GDSC2	4.6025	7.7413	2.0665	4.8998
MDA-MB-468	GDSC2	4.6298	7.6999	2.1032	4.6351
CAL-148	GDSC2	4.6385	6.2194	2.7677	1.0743
MDA-MB-436	GDSC2	4.6564	7.1142	2.3886	2.9731
HCC1419	GDSC2	4.7786	8.044	2.0363	4.7449
HCC1806	GDSC2	4.8653	8.8514	1.7133	6.4426
EFM-19	GDSC2	4.8958	7.5108	2.3481	2.8207
MFM-223	GDSC2	4.954	6.6456	2.7434	0.8758
BT-483	GDSC2	4.9705	10.6113	0.9429	10.6129
HCC1187	GDSC2	5.0738	7.9284	2.2628	3.0081
MCF-7	GDSC2	5.0837	6.7766	2.7497	0.7483
HCC1937	GDSC2	5.1578	7.4947	2.494	1.7481
HCC1500	GDSC2	5.3988	7.3821	2.6521	0.8648
JIMT-1	GDSC2	5.4086	6.7285	2.8963	0.184
HCC2218	GDSC2	5.4799	7.5818	2.61	0.9566
EFM-192A	GDSC2	5.5523	7.3802	2.7173	0.5531
HCC38	GDSC2	5.5698	7.9885	2.4897	1.3476
UACC-812	GDSC2	5.6726	7.7612	2.6238	0.7724
HCC1954	GDSC2	5.7388	7.4072	2.7801	0.3095
BT-20	GDSC2	5.8568	7.2483	2.8772	0.115
UACC-893	GDSC2	5.9259	8.153	2.5813	0.7507
HCC1143	GDSC2	6.3341	8.497	2.6168	0.4527
T-47D	GDSC2	6.3349	8.5784	2.5879	0.5222
CAL-85-1	GDSC2	6.3857	8.9153	2.4844	0.7801

Cancer Drug Sensitivity Data Curated from 54 Cell Line(s) in Central Nervous System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
D283 Med	GDSC2	3.1442	5.5487	2.0571	8.5388
AM-38	GDSC2	3.8446	7.9609	1.4224	10.521
D-566MG	GDSC2	4.0678	5.9598	2.5607	3.0337
MOG-G-UVW	GDSC2	4.0773	6.3303	2.3912	4.0245
8-MG-BA	GDSC2	4.1127	5.9575	2.5904	2.774
H4	GDSC2	4.1176	6.6716	2.2549	4.7619
A-172	GDSC2	4.1182	7.8074	1.7032	8.1252
YH-13	GDSC2	4.1714	6.0037	2.6055	2.5796
NMC-G1	GDSC2	4.1929	6.1245	2.5629	2.7857
Onda 10	GDSC2	4.201	7.486	1.9192	6.6171
PFSK-1	GDSC2	4.2094	8.5063	1.427	9.5748
MOG-G-CCM	GDSC2	4.2155	6.8317	2.2443	4.6193
SW1783	GDSC2	4.3044	9.6262	0.9464	12.1512
SW1088	GDSC2	4.4212	6.4325	2.5591	2.4164
42-MG-BA	GDSC2	4.4236	7.1098	2.2486	4.1797
D-542MG	GDSC2	4.48	9.6604	1.0583	11.0853
D-247MG	GDSC2	4.5214	7.1085	2.3104	3.6414
SK-MG-1	GDSC2	4.6051	6.609	2.5844	2.0049
Onda 11	GDSC2	4.6068	8.5177	1.7011	7.0409
LN-18	GDSC2	4.6287	5.6476	2.9869	0.2699
GB-1	GDSC2	4.6327	6.2862	2.7371	1.2192
YKG-1	GDSC2	4.6672	6.4643	2.6797	1.4486
CAS-1	GDSC2	4.6852	6.3777	2.725	1.216
GaMG	GDSC2	4.7394	9.6857	1.2299	9.5044
Becker	GDSC2	4.7425	6.4854	2.7086	1.228
DK-MG	GDSC2	4.7522	6.4801	2.7155	1.1864
KS-1 [Human Krukenberg tumour]	GDSC2	4.7663	7.5191	2.2699	3.4483
SF295	GDSC2	4.8096	6.3276	2.8041	0.7613
ONS-76	GDSC2	4.819	7.2487	2.4212	2.5488
Hs 683	GDSC2	4.8536	6.4463	2.777	0.83
SF539	GDSC2	4.872	6.7716	2.6536	1.3358
D-263MG	GDSC2	4.8976	7.4847	2.3607	2.7518
T98G	GDSC2	4.9113	7.6884	2.2778	3.1729
U-87MG ATCC	GDSC2	4.9161	6.3337	2.848	0.5252
D-336MG	GDSC2	4.9741	8.4395	1.9739	4.7488
LN-229	GDSC2	4.9782	8.2654	2.0561	4.281
D-502MG	GDSC2	5.1891	8.0591	2.2689	2.812
U-118MG	GDSC2	5.2223	8.6498	2.0256	4.0478
U-251MG	GDSC2	5.3105	6.5951	2.907	0.1924
DBTRG-05MG	GDSC2	5.4586	7.1987	2.7467	0.518
LN-405	GDSC2	5.4716	6.8619	2.8728	0.209
KNS-81-FD	GDSC2	5.503	8.3345	2.3153	2.1836
SF268	GDSC2	5.5111	7.617	2.61	0.9328
GI-1	GDSC2	5.5145	7.3906	2.698	0.6331
Daoy	GDSC2	5.5222	7.2315	2.76	0.4484
M059J	GDSC2	5.5323	8.5888	2.2225	2.5908
D-423MG	GDSC2	5.573	8.6217	2.2295	2.5068
KNS-42	GDSC2	5.6775	7.0627	2.8775	0.1491
D-392MG	GDSC2	5.8191	8.2395	2.5027	1.09
SNB-75	GDSC2	5.8405	7.6531	2.7309	0.3819
KALS-1	GDSC2	5.8607	13.2719	0.2705	12.245
D-245MG	GDSC2	5.9132	8.6443	2.3854	1.4614
SF126	GDSC2	5.979	7.539	2.8215	0.1668
KINGS-1	GDSC2	6.4357	8.7	2.5828	0.492

Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
ETK-1	GDSC2	3.9988	6.6503	2.1825	5.4662
TGBC24TKB	GDSC2	4.0977	7.2424	1.9646	6.5762
TGBC1TKB	GDSC2	4.2524	6.9209	2.2263	4.6509

Cancer Drug Sensitivity Data Curated from 8 Cell Line(s) in Endometrium Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
EN	GDSC2	3.9585	5.8281	2.5514	3.3088
KLE	GDSC2	4.1386	6.6502	2.2794	4.5692
RL95-2	GDSC2	4.5148	6.8316	2.4334	2.9581
MFE-319	GDSC2	4.5259	7.4273	2.1649	4.473
ESS-1	GDSC2	4.6539	6.5191	2.6494	1.6115
MFE-280	GDSC2	4.8299	10.4476	0.9242	11.0303
MFE-296	GDSC2	5.8702	7.5778	2.7687	0.2884
AN3-CA	GDSC2	6.8481	20.1354	-2.3583	20.7223

Cancer Drug Sensitivity Data Curated from 33 Cell Line(s) in Kidney Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
KTCTL-13	GDSC2	3.7766	6.2691	2.2079	5.8353
BFTC-909	GDSC2	3.802	5.7676	2.4724	4.1329
786-O	GDSC2	3.8989	5.6619	2.5908	3.1957
ACHN	GDSC2	3.9174	6.1104	2.3874	4.3936
Caki-1	GDSC2	4.0791	8.4135	1.3764	10.1982
SW13	GDSC2	4.0964	6.8796	2.1399	5.5072
CAL-54	GDSC2	4.1139	18.5909	-3.663	30.1737
A-498	GDSC2	4.1419	7.7969	1.7255	7.9331
RCC10RGB	GDSC2	4.1441	7.7588	1.7457	7.805
KMRC-1	GDSC2	4.192	7.0741	2.1121	5.4658
KTCTL-140	GDSC2	4.296	7.1864	2.1288	5.1445
NCC021	GDSC2	4.3303	7.2189	2.1362	5.029
VMRC-RCW	GDSC2	4.3473	7.5682	1.9806	5.9254
A-704	GDSC2	4.3522	10.4236	0.5889	14.0161
SN12C	GDSC2	4.4032	7.3926	2.1018	5.0851
NCC010	GDSC2	4.4285	7.6372	2.0022	5.6256
TK-10	GDSC2	4.6152	9.0215	1.4647	8.4155
VMRC-RCZ	GDSC2	4.6228	7.4598	2.2105	4.0305
BB65-RCC	GDSC2	4.6262	7.0686	2.3916	3.0062
HA7-RCC	GDSC2	4.9113	9.2004	1.5783	7.131
769-P	GDSC2	4.9237	9.05	1.6575	6.6503
UO-31	GDSC2	5.0358	7.2762	2.5244	1.7471
KTCTL-195	GDSC2	5.0598	8.3563	2.0632	4.1053
KTCTL-26A	GDSC2	5.0796	7.6708	2.3786	2.404
RXF 393L	GDSC2	5.082	8.7041	1.9178	4.8752
KMRC-20	GDSC2	5.2977	7.0245	2.746	0.6139
KTCTL-21	GDSC2	5.3798	8.7232	2.0822	3.5064
LB2241-RCC	GDSC2	5.5286	7.6053	2.6221	0.8765
OS-RC-2	GDSC2	5.5762	7.5599	2.6597	0.7169
LB996-RCC	GDSC2	5.8499	7.7965	2.6827	0.4982
SW156	GDSC2	6.1498	8.4731	2.5532	0.7074
LB1047-RCC	GDSC2	6.3441	8.4965	2.6208	0.4395
KTCTL-1M	GDSC2	6.6323	8.7359	2.6434	0.2979

Cancer Drug Sensitivity Data Curated from 46 Cell Line(s) in Large Intestine Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HT-29	GDSC2	3.4243	5.2237	2.455	5.1987
HCT 116	GDSC2	3.6449	5.6973	2.3915	5.0158
RKO	GDSC2	3.7461	6.8212	1.912	7.7588
COLO 320HSR	GDSC2	3.7619	6.558	2.0543	6.8307
NCI-H508	GDSC2	3.8286	5.469	2.6357	3.0739
LS411N	GDSC2	3.8391	9.3179	0.7433	14.5124
SW48	GDSC2	3.8708	12.4886	-0.8124	22.0156
HCC2998	GDSC2	3.9698	5.9411	2.505	3.5645
COLO205	GDSC2	3.9821	6.4243	2.2805	4.903
MDST8	GDSC2	3.9887	6.2573	2.3659	4.3667
LS123	GDSC2	4.0264	7.8149	1.6321	8.7816
NCI-H747	GDSC2	4.0586	6.2806	2.4024	3.9962
SNU-175	GDSC2	4.0629	6.0781	2.5016	3.3932
SK-CO-1	GDSC2	4.0915	6.6077	2.2677	4.7403
SW837	GDSC2	4.1447	7.1081	2.063	5.8684
RCM-1 [Human ESC]	GDSC2	4.1594	6.8306	2.2069	4.9623
SNU-C1	GDSC2	4.1804	6.1496	2.5434	2.9206
CCK-81	GDSC2	4.1942	6.6786	2.3031	4.3111
SNU-C5	GDSC2	4.3513	7.6584	1.94	6.1607
C2BBe1	GDSC2	4.3819	6.9992	2.2738	4.1122
HCT 15	GDSC2	4.3887	7.0411	2.2584	4.189
SW626	GDSC2	4.5743	7.5555	2.1356	4.5517
KM12	GDSC2	4.5775	6.5793	2.5823	2.0551
SW948	GDSC2	4.593	6.798	2.4941	2.4998
CaR-1	GDSC2	4.6295	6.6975	2.559	2.1018
SNU-81	GDSC2	4.7701	7.0635	2.4756	2.335
LS1034	GDSC2	4.8366	7.7393	2.2115	3.6554
SW1463	GDSC2	4.8778	6.8648	2.6176	1.4941
GP5d	GDSC2	4.9037	6.8948	2.618	1.463
SW620	GDSC2	4.9245	7.0996	2.5423	1.7954
DiFi	GDSC2	4.957	7.4696	2.4	2.462
COLO 678	GDSC2	4.9924	7.0355	2.6033	1.4322
LS180	GDSC2	5.0183	7.5023	2.4188	2.2834
SNU-407	GDSC2	5.0323	7.2693	2.5256	1.7458
SW1116	GDSC2	5.1043	6.9854	2.6767	1.0095
SW1417	GDSC2	5.1847	7.6034	2.462	1.8666
HT115	GDSC2	5.2096	6.8327	2.7818	0.5544
SNU-283	GDSC2	5.3311	8.3188	2.2325	2.8027
SNU-61	GDSC2	5.3706	7.2231	2.7012	0.7139
HT-55	GDSC2	5.6106	7.2063	2.8032	0.3053
SNU-C2B	GDSC2	5.666	8.3628	2.3835	1.7005
CW-2	GDSC2	5.7151	7.8798	2.5965	0.835
LoVo	GDSC2	5.8379	7.8568	2.6558	0.5779
CL-11	GDSC2	6.1232	7.9221	2.7412	0.264
NCI-H716	GDSC2	6.2128	7.9521	2.763	0.2034
T84	GDSC2	6.4679	8.3525	2.7165	0.217

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
MO-T	GDSC2	5.728	7.367	2.7902	0.2917

Cancer Drug Sensitivity Data Curated from 15 Cell Line(s) in Liver Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
JHH-6	GDSC2	3.6223	5.7439	2.3513	5.3254
SK-HEP-1	GDSC2	3.9134	6.0694	2.4044	4.2983
SNU-387	GDSC2	4.0364	6.7432	2.164	5.4944
Hep 3B2.1-7	GDSC2	4.0641	16.0223	-2.4208	27.1114
SNU-423	GDSC2	4.4267	11.8439	-0.057	17.1366
JHH-1	GDSC2	4.6741	6.3457	2.7329	1.1927
HLE	GDSC2	4.9765	7.6959	2.3113	2.8958
JHH-4	GDSC2	5.062	9.5642	1.5045	7.2542
Hep-G2/C3A	GDSC2	5.2127	6.4805	2.9112	0.2145
JHH-2	GDSC2	5.2336	8.8151	1.9575	4.3996
JHH-7	GDSC2	5.4324	7.4805	2.6286	0.9248
HuH-1	GDSC2	5.4969	7.1334	2.7858	0.3926
SNU-398	GDSC2	5.5252	7.3915	2.702	0.6141
Huh-7	GDSC2	5.7432	7.3886	2.7882	0.2906
SNU-449	GDSC2	6.0582	7.7281	2.7848	0.2055

Cancer Drug Sensitivity Data Curated from 182 Cell Line(s) in Lung Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
NCI-H835	GDSC2	2.1804	5.1899	1.3237	16.3936
IST-SL2	GDSC2	2.8273	6.7051	1.2023	14.849
COR-L303	GDSC2	3.0389	5.166	2.1545	8.2571
NCI-H211	GDSC2	3.2488	4.6198	2.6111	4.7181
IST-SL1	GDSC2	3.2535	5.4296	2.2105	7.238
NCI-H69	GDSC2	3.2629	5.4983	2.1842	7.3765
NCI-H526	GDSC2	3.2721	4.8321	2.5249	5.1929
NCI-H292	GDSC2	3.3784	4.7786	2.6401	4.1559
HCC78	GDSC2	3.425	7.1873	1.4745	11.3529
NCI-H82	GDSC2	3.4287	5.6746	2.2333	6.5876
EBC-1	GDSC2	3.4342	5.505	2.3225	6.0084
COR-L279	GDSC2	3.5319	5.3989	2.4528	4.9222
Lu-65	GDSC2	3.5558	6.1842	2.0808	7.202
DMS 273	GDSC2	3.5707	6.6373	1.8668	8.5057
NCI-H1963	GDSC2	3.5896	6.8564	1.7725	9.044
RERF-LC-MS	GDSC2	3.6021	7.0529	1.6845	9.5581
NCI-H740	GDSC2	3.606	6.0238	2.1998	6.3192
NCI-H2196	GDSC2	3.6223	6.8444	1.8044	8.7565
SBC-3	GDSC2	3.6254	5.6161	2.4169	4.9065
COR-L105	GDSC2	3.633	10.2465	0.1154	18.4377
NCI-H146	GDSC2	3.6906	5.3605	2.5912	3.6587
NCI-H2810	GDSC2	3.7182	5.8229	2.3844	4.8787
COR-L32	GDSC2	3.7222	6.2497	2.1767	6.1658
NCI-H647	GDSC2	3.7377	5.6378	2.4895	4.1776
NCI-H250	GDSC2	3.7427	7.2456	1.6988	9.0933
NCI-H64	GDSC2	3.7739	5.1942	2.7304	2.617
COR-L88	GDSC2	3.7935	6.635	2.0401	6.84
NCI-H226	GDSC2	3.7979	6.8697	1.9274	7.5305
NCI-H1648	GDSC2	3.8292	6.5608	2.1034	6.3571
NCI-H1734	GDSC2	3.8408	7.4113	1.6919	8.8809
Ms-1	GDSC2	3.8493	5.6063	2.5838	3.3445
HARA [Human squamous cell lung carcinoma]	GDSC2	3.8523	5.9598	2.4146	4.3736
NCI-H2795	GDSC2	3.8645	6.8865	1.9691	7.1045
ChaGo-K-1	GDSC2	3.8951	6.4031	2.229	5.4199
EPLC-272H	GDSC2	3.898	10.0312	0.4345	16.04
NCI-H2171	GDSC2	3.9114	6.6009	2.1439	5.9073
NCI-H1915	GDSC2	3.9168	6.1089	2.3877	4.393
NCI-H1155	GDSC2	3.9263	5.8584	2.5152	3.5948
EMC-BAC-2	GDSC2	3.9281	6.6357	2.139	5.8983
BEN	GDSC2	3.9286	13.3971	-1.2195	23.4696
LCLC-97TM1	GDSC2	3.9465	7.5423	1.7069	8.5215
SHP-77	GDSC2	3.9472	9.8189	0.5787	15.1288
LB647-SCLC	GDSC2	3.957	6.4867	2.2325	5.2549
NCI-H2444	GDSC2	3.9763	7.8368	1.5839	9.2
NCI-H524	GDSC2	3.9816	6.1837	2.3965	4.1963
RERF-LC-Sq1	GDSC2	3.9875	9.0881	0.973	12.8081
NCI-H847	GDSC2	4.0057	5.7238	2.6318	2.7353
LC-1/sq	GDSC2	4.013	6.7486	2.1448	5.6652
NCI-H810	GDSC2	4.021	5.9329	2.5429	3.2315
LCLC-103H	GDSC2	4.0359	6.0002	2.5209	3.3326
NCI-H1975	GDSC2	4.0367	6.907	2.0845	5.9812
NCI-H1581	GDSC2	4.051	5.7485	2.6491	2.5483
NCI-H838	GDSC2	4.0554	8.4509	1.3401	10.4753
COR-L321	GDSC2	4.0644	6.5411	2.2812	4.7169
NCI-H460	GDSC2	4.0834	5.8098	2.6408	2.536
CPC-N	GDSC2	4.0874	6.9361	2.1062	5.7329
NCI-H1703	GDSC2	4.1179	8.0898	1.5644	8.9692
NCI-H1836	GDSC2	4.1332	6.052	2.5592	2.9169
DMS 114	GDSC2	4.1567	6.729	2.2539	4.6848
NCI-H358	GDSC2	4.1595	9.5105	0.8949	12.8091
NCI-H1437	GDSC2	4.1606	6.365	2.4297	3.6252
NCI-H1666	GDSC2	4.1668	10.156	0.581	14.5343
NCI-H2122	GDSC2	4.1802	5.9261	2.6465	2.3311
NCI-H1563	GDSC2	4.1892	7.3858	1.9595	6.3989
IA-LM	GDSC2	4.198	7.7616	1.7831	7.452
COLO 668	GDSC2	4.2139	9.0377	1.169	11.0909
NCI-H2461	GDSC2	4.2332	10.2934	0.5634	14.4572
NCI-H748	GDSC2	4.2579	6.337	2.5047	3.0022
NCI-H2110	GDSC2	4.2622	7.4896	1.9601	6.233
NCI-H2804	GDSC2	4.2637	8.7175	1.3631	9.8246
LOU-NH91	GDSC2	4.2692	6.6271	2.3763	3.7279
NCI-H290	GDSC2	4.2931	9.8454	0.8299	12.837
NCI-H2170	GDSC2	4.3121	6.9878	2.234	4.4839
NCI-H3255	GDSC2	4.3231	7.8124	1.8464	6.7855
HCC44	GDSC2	4.3317	7.0838	2.2013	4.6385
NCI-H2818	GDSC2	4.3659	6.8831	2.318	3.8841
NCI-H196	GDSC2	4.3742	6.2678	2.606	2.2351
NCI-H1755	GDSC2	4.3819	9.5606	1.0358	11.4498
NCI-H2081	GDSC2	4.3843	6.8972	2.3231	3.8196
Lu-135	GDSC2	4.3866	6.3271	2.5865	2.3222
NCI-H2009	GDSC2	4.3982	10.4627	0.604	13.819
NCI-H727	GDSC2	4.4183	6.5032	2.5254	2.6071
A-549	GDSC2	4.4205	7.367	2.1253	4.9106
NCI-H520	GDSC2	4.4494	10.4568	0.645	13.4692
NCI-H2369	GDSC2	4.4515	6.7499	2.4328	3.069
NCI-H1436	GDSC2	4.509	6.6243	2.5237	2.4705
COR-L23	GDSC2	4.5236	6.0759	2.7705	1.1886
HCC33	GDSC2	4.5338	6.3724	2.6489	1.7724
Lu-165	GDSC2	4.5545	6.995	2.3826	3.1751
NCI-H345	GDSC2	4.5624	5.596	2.9793	0.3264
NCI-H1693	GDSC2	4.5716	6.8654	2.4515	2.7652
NCI-H2030	GDSC2	4.5802	6.6496	2.5528	2.2059
NCI-H1435	GDSC2	4.5885	8.5136	1.6907	7.1409
PC-14	GDSC2	4.5911	6.5465	2.6041	1.923
NCI-H841	GDSC2	4.601	7.4115	2.2194	4.019
SBC-5	GDSC2	4.6119	6.1184	2.7963	0.976
NCI-H1944	GDSC2	4.6311	7.385	2.25	3.7905
NCI-H2731	GDSC2	4.6677	7.1779	2.3665	3.0766
NCI-H1792	GDSC2	4.6961	7.6284	2.1776	4.0868
NCI-H510A	GDSC2	4.7352	6.5085	2.6954	1.2962
COR-L311	GDSC2	4.7554	6.8825	2.5466	1.9911
NCI-H2141	GDSC2	4.7629	6.6851	2.6351	1.5464
NCI-H1838	GDSC2	4.7678	6.8521	2.5663	1.8759
NCI-H1793	GDSC2	4.7886	10.2131	1.0089	10.6505
NCI-H1781	GDSC2	4.8238	6.29	2.8251	0.6707
NCI-H2228	GDSC2	4.8648	7.9319	2.1405	4.0031
VMRC-LCD	GDSC2	4.879	12.0599	0.1728	14.8907
LK-2	GDSC2	4.9372	8.5166	1.9155	5.1453
KNS-62	GDSC2	4.9436	13.0986	-0.2896	16.9551
NCI-H1105	GDSC2	4.944	6.6922	2.7203	0.9772
NCI-H1993	GDSC2	4.9861	7.4092	2.4419	2.2104
NCI-H522	GDSC2	5.0021	7.0255	2.6122	1.3817
NCI-H2029	GDSC2	5.0029	6.9159	2.6575	1.1833
PaCa-3	GDSC2	5.0201	9.9334	1.3019	8.4919
NCI-H322M	GDSC2	5.042	8.1948	2.1258	3.791
NCI-H2135	GDSC2	5.0444	6.8056	2.7209	0.8872
UMC-11	GDSC2	5.0464	7.0185	2.6364	1.2308
NCI-H720	GDSC2	5.0656	6.1763	2.9636	0.1586
NCI-H2722	GDSC2	5.0921	6.8551	2.7228	0.8412
NCI-H2595	GDSC2	5.1168	7.5734	2.44	2.0529
SK-LU-1	GDSC2	5.1388	8.3751	2.1008	3.7732
SK-MES-1	GDSC2	5.1428	7.9084	2.3094	2.6688
NCI-H1092	GDSC2	5.1438	7.2715	2.5796	1.3782
NCI-H2066	GDSC2	5.1492	6.9894	2.6954	0.8986
NCI-H2869	GDSC2	5.15	7.2572	2.5884	1.3337
NCI-H441	GDSC2	5.1535	7.0564	2.6709	0.9899
NCI-H1869	GDSC2	5.1594	7.1905	2.6199	1.1911
ABC-1	GDSC2	5.1706	9.0006	1.8354	5.1808
NCI-H1651	GDSC2	5.1848	8.1107	2.2439	2.9465
NCI-H2085	GDSC2	5.1893	7.1207	2.6616	0.9958
SBC-1	GDSC2	5.2016	17.4497	-2.2432	23.822
Calu-3	GDSC2	5.2063	7.49	2.52	1.5761
NCI-H2373	GDSC2	5.2125	6.9442	2.7406	0.6876
NCI-H2347	GDSC2	5.2451	7.8723	2.3791	2.1891
NCI-H1341	GDSC2	5.2778	6.7484	2.8402	0.3521
NCI-H2087	GDSC2	5.2864	7.9158	2.3818	2.1254
NCI-H661	GDSC2	5.298	7.5179	2.5526	1.3411
SW1271	GDSC2	5.3251	7.2855	2.6575	0.9013
RERF-LC-KJ	GDSC2	5.3406	6.865	2.8224	0.3694
NCI-H1299	GDSC2	5.3571	14.9782	-0.9093	18.6739
NCI-H1573	GDSC2	5.3622	7.2664	2.681	0.789
NCI-H2803	GDSC2	5.3962	7.4533	2.6233	0.9727
NCI-H1770	GDSC2	5.4175	6.8173	2.8686	0.234
NCI-H1568	GDSC2	5.4921	7.5722	2.6191	0.9142
NCI-H2405	GDSC2	5.5031	8.6068	2.1996	2.7403
LC-2/ad	GDSC2	5.5031	8.1512	2.3917	1.8328
NCI-H446	GDSC2	5.5326	7.3012	2.7386	0.5022
HCC366	GDSC2	5.5351	19.0932	-2.8038	24.75
DMS 79	GDSC2	5.5394	7.3176	2.7352	0.5082
Calu-6	GDSC2	5.5431	7.0851	2.8208	0.2911
NCI-H596	GDSC2	5.563	6.9854	2.8632	0.2006
NCI-H2291	GDSC2	5.5662	7.3496	2.7342	0.4974
CAL-12T	GDSC2	5.5677	8.3396	2.3454	1.9718
HCC827	GDSC2	5.5829	7.5054	2.683	0.6389
NCI-H3122	GDSC2	5.6019	7.7491	2.5983	0.9079
NCI-H1355	GDSC2	5.6071	7.8432	2.564	1.0277
NCI-H1623	GDSC2	5.6733	7.5402	2.7067	0.5195
NCI-H2023	GDSC2	5.6851	7.336	2.7851	0.3179
Lu-134-A	GDSC2	5.7035	8.7023	2.2616	2.203
A-427	GDSC2	5.7335	14.0358	-0.1827	14.6744
EKVX	GDSC2	5.7429	8.6167	2.3165	1.9137
HOP-62	GDSC2	5.7519	7.6984	2.6798	0.5547
NCI-H1048	GDSC2	5.7549	7.2457	2.8423	0.1862
NCI-H513	GDSC2	5.7635	7.5436	2.7407	0.3898
NCI-H2342	GDSC2	5.794	7.8402	2.6443	0.6351
NCI-H1694	GDSC2	5.8771	7.7122	2.7236	0.3843
NCI-H1876	GDSC2	5.8984	7.6409	2.757	0.303
DMS 53	GDSC2	5.902	7.7123	2.733	0.3533
EMC-BAC-1	GDSC2	5.9073	8.3393	2.5024	1.0256
Lu-99A	GDSC2	5.9677	8.5014	2.4659	1.1113
NCI-H209	GDSC2	5.975	7.6989	2.7649	0.2631
NCI-H2172	GDSC2	5.9875	7.5456	2.8222	0.1639
NCI-H650	GDSC2	6.0489	7.569	2.8357	0.1335
HCC15	GDSC2	6.0578	7.8777	2.7327	0.3001
LXF 289	GDSC2	6.0622	7.9392	2.7127	0.3399
NCI-H2227	GDSC2	6.1196	17.8865	-1.7809	20.2836
NCI-H1688	GDSC2	6.158	8.1261	2.6824	0.3712
HOP-92	GDSC2	6.1635	8.5251	2.5394	0.7407
NCI-H23	GDSC2	6.1755	8.1169	2.6922	0.3442
NCI-H2591	GDSC2	6.2467	8.186	2.6942	0.3165
NCI-H1650	GDSC2	6.4902	8.4409	2.6941	0.2477
SW1573	GDSC2	6.51	8.9016	2.5387	0.5688

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
CBTCi002-A	GDSC2	3.1881	4.5959	2.5702	5.1631

Cancer Drug Sensitivity Data Curated from 23 Cell Line(s) in Oesophagus Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
OE19	GDSC2	3.5378	5.8297	2.2431	6.2279
KYSE-140	GDSC2	3.5964	6.4764	1.9672	7.807
T.T	GDSC2	3.7616	6.1284	2.2661	5.5097
OE21	GDSC2	3.9871	6.8543	2.0747	6.1566
KYSE-450	GDSC2	4.0037	6.7196	2.1523	5.6406
KYSE-270	GDSC2	4.0841	6.1761	2.4691	3.5437
TE-6	GDSC2	4.2989	8.0962	1.6919	7.7721
KYSE-150	GDSC2	4.415	8.3647	1.6432	7.8018
TE-5	GDSC2	4.4905	7.5808	2.0699	5.099
COLO 680N	GDSC2	4.5697	6.7306	2.5109	2.4454
OE33	GDSC2	4.5902	10.3673	0.7922	12.3193
TE-8	GDSC2	4.8603	7.3637	2.3933	2.6347
EC-GI-10	GDSC2	4.8784	7.5262	2.3315	2.9355
KYSE-520	GDSC2	4.9035	7.302	2.4441	2.3104
KYSE-410	GDSC2	5.0855	7.5908	2.4163	2.2083
KYSE-510	GDSC2	5.1406	9.9605	1.3684	7.8706
TE-4	GDSC2	5.2062	7.1057	2.6751	0.9295
KYSE-180	GDSC2	5.2168	7.2091	2.639	1.0613
TE-11	GDSC2	5.3824	7.5253	2.5887	1.1169
KYSE-70	GDSC2	5.7055	13.3315	0.1373	13.2174
TE-1	GDSC2	5.7343	7.6294	2.6982	0.5124
TE-9	GDSC2	5.8151	7.4644	2.7882	0.2672
TE-10	GDSC2	5.9342	7.7002	2.7494	0.3067

Cancer Drug Sensitivity Data Curated from 30 Cell Line(s) in Ovary Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
JHOS-4	GDSC2	3.5603	8.4761	0.9407	14.1641
A2780	GDSC2	3.7958	8.8758	0.9293	13.5734
OC 314	GDSC2	3.852	5.9663	2.4112	4.3951
TYK-nu	GDSC2	3.9234	7.1873	1.8647	7.6059
TOV-21G	GDSC2	3.9893	6.7055	2.1489	5.6943
OV56	GDSC2	4.035	6.5359	2.2634	4.8896
OV-90	GDSC2	4.0846	6.7285	2.2047	5.1381
Caov-4	GDSC2	4.0918	6.1655	2.4792	3.4687
DOV13	GDSC2	4.1	7.9307	1.6294	8.6181
RMG-I	GDSC2	4.102	8.4482	1.3763	10.1415
OVISE	GDSC2	4.1318	6.345	2.4204	3.7382
IGROV-1	GDSC2	4.137	6.7322	2.2389	4.8169
JHOS-2	GDSC2	4.3252	6.9535	2.2587	4.3111
OVKATE	GDSC2	4.4349	7.2157	2.206	4.4072
FU-OV-1	GDSC2	4.444	10.1618	0.7861	12.7069
OVK18	GDSC2	4.4768	8.6607	1.543	8.2603
EFO-27	GDSC2	4.6682	7.2597	2.3297	3.2795
OAW28	GDSC2	4.7257	8.0357	2.007	5.0118
OVCAR-5	GDSC2	4.7625	7.2693	2.3802	2.8519
OVCAR-3	GDSC2	4.8113	6.6438	2.6767	1.2974
OVCAR-8	GDSC2	4.8807	8.293	1.9841	4.8575
TOV-112D	GDSC2	4.9638	7.7356	2.2866	3.0455
OVTOKO	GDSC2	4.9915	10.675	0.9266	10.6569
OVCAR-4	GDSC2	5.0111	10.4012	1.0719	9.807
Kuramochi	GDSC2	5.0417	7.7481	2.3244	2.7328
Caov-3	GDSC2	5.0709	7.1217	2.6059	1.3378
SK-OV-3	GDSC2	5.1094	7.0629	2.6481	1.1212
OAW42	GDSC2	5.2083	6.247	2.9899	0.0869
EFO-21	GDSC2	5.2156	11.8181	0.5297	12.296
ES-2	GDSC2	5.4052	6.849	2.8528	0.2712

Cancer Drug Sensitivity Data Curated from 31 Cell Line(s) in Pancreas Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
Panc 02.03	GDSC2	3.7151	6.4262	2.084	6.7636
HuP-T3	GDSC2	3.8752	6.4234	2.2046	5.6175
PSN1	GDSC2	4.1907	6.2835	2.4874	3.2277
Hs 766T	GDSC2	4.2837	11.8008	-0.1451	17.9295
PaTu 8988t	GDSC2	4.3058	6.2077	2.5932	2.4172
HPAC	GDSC2	4.3161	7.1106	2.1783	4.8067
Capan-1	GDSC2	4.3476	6.4327	2.5154	2.7822
MIA PaCa-2	GDSC2	4.4213	8.4863	1.5887	8.1131
BxPC-3	GDSC2	4.4446	6.7944	2.4082	3.2204
Panc 03.27	GDSC2	4.4799	6.8698	2.395	3.2337
PaTu 8902	GDSC2	4.5032	6.7976	2.4419	2.9301
YAPC	GDSC2	4.5382	9.5094	1.1739	10.2835
PL4	GDSC2	4.5824	6.6463	2.5555	2.1887
DAN-G	GDSC2	4.6656	5.9623	2.8834	0.5784
KP-3	GDSC2	4.803	7.812	2.1582	4.0092
SU.86.86	GDSC2	4.8133	6.19	2.8593	0.5565
Panc 04.03	GDSC2	4.8381	6.9946	2.5421	1.9047
KP-4	GDSC2	5.0102	7.5739	2.3834	2.4735
Capan-2	GDSC2	5.0209	7.2715	2.5188	1.7911
HPAF-II	GDSC2	5.4778	8.3175	2.3096	2.2399
SW1990	GDSC2	5.5524	11.368	0.9713	9.2468
KP-2	GDSC2	5.6712	6.8836	2.9356	0.0778
HuP-T4	GDSC2	5.7742	7.6121	2.7201	0.436
AsPC-1	GDSC2	5.809	13.0044	0.3636	11.8888
Panc 10.05	GDSC2	5.8141	8.6328	2.3439	1.7234
Panc 08.13	GDSC2	5.8934	7.8372	2.6849	0.4724
CFPAC-1	GDSC2	5.9093	7.5213	2.8027	0.2133
SUIT-2	GDSC2	5.9391	7.427	2.8455	0.141
QGP-1	GDSC2	5.953	16.6282	-1.2863	18.8406
KP-1N	GDSC2	6.1252	8.0586	2.694	0.3577
MZ-PC-1	GDSC2	6.221	8.4785	2.5796	0.5959

Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Pleura Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
IST-Mes1	GDSC2	3.7482	6.4577	2.0936	6.6198
MPP 89	GDSC2	3.828	9.8328	0.4781	15.9993
NCI-H2452	GDSC2	4.2393	6.69	2.3274	4.0753
MSTO-211H	GDSC2	4.6283	19.6685	-3.7898	29.2662
NCI-H2052	GDSC2	5.3455	7.5541	2.5602	1.2645
NCI-H28	GDSC2	5.7775	7.7617	2.6667	0.5785

Cancer Drug Sensitivity Data Curated from 6 Cell Line(s) in Prostate Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
VCaP	GDSC2	3.8663	6.9476	1.9403	7.279
LNCaP clone FGC	GDSC2	3.8753	6.659	2.0891	6.3339
NCI-H660	GDSC2	4.8313	6.4048	2.7833	0.8242
22Rv1	GDSC2	5.101	7.3026	2.5459	1.5734
PC-3	GDSC2	6.0678	8.2981	2.5849	0.6593
DU145	GDSC2	6.1246	8.2572	2.6225	0.528

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
A-253	GDSC2	4.285	7.4484	1.9957	5.9681

Cancer Drug Sensitivity Data Curated from 57 Cell Line(s) in Skin Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
COLO 783	GDSC2	3.3527	5.0204	2.4982	5.1269
LOX-IMVI	GDSC2	3.4667	6.4117	1.896	8.6088
COLO 792	GDSC2	3.5139	5.0866	2.594	4.0798
A101D	GDSC2	3.6867	5.2498	2.6425	3.35
IPC-298	GDSC2	3.715	5.3661	2.606	3.5101
HT-144	GDSC2	3.73	9.8699	0.3814	16.7881
SK-MEL-28	GDSC2	3.7894	11.192	-0.2307	19.6756
VMRC-MELG	GDSC2	3.7959	9.0182	0.8585	13.9792
UACC-62	GDSC2	3.8046	5.537	2.5863	3.427
A2058	GDSC2	3.9476	5.5784	2.6628	2.6663
MZ-MEL-7	GDSC2	3.9925	6.1946	2.3987	4.1591
SK-MEL-3	GDSC2	4.0001	6.6373	2.1898	5.4186
SK-MEL-30	GDSC2	4.0173	5.8174	2.5952	2.9288
Hs 940.T	GDSC2	4.109	9.2437	0.9886	12.4027
Mel JuSo	GDSC2	4.1216	7.3383	1.9349	6.7023
M14	GDSC2	4.1276	6.799	2.2004	5.0703
G-mel	GDSC2	4.1504	6.3798	2.4161	3.7264
COLO 829	GDSC2	4.1699	6.4715	2.3854	3.8698
WM793	GDSC2	4.2094	6.1446	2.5638	2.7505
SH-4	GDSC2	4.2454	8.3521	1.5288	8.8785
MeWo	GDSC2	4.2626	6.406	2.4756	3.1616
MZ-MEL-2	GDSC2	4.3121	7.3601	2.0566	5.5439
RPMI-7951	GDSC2	4.3803	6.4932	2.5074	2.7714
451Lu	GDSC2	4.4115	8.6122	1.5206	8.5407
IGR-37	GDSC2	4.4331	5.9416	2.7812	1.2456
Mel Ho	GDSC2	4.4387	6.1348	2.701	1.6371
IGR-1	GDSC2	4.4747	6.7664	2.4392	2.9935
Hs 938.T	GDSC2	4.5009	6.4702	2.5878	2.1382
A-375	GDSC2	4.5074	6.3316	2.6524	1.7912
WM278	GDSC2	4.5132	8.1741	1.8024	6.6382
RVH-421	GDSC2	4.5333	7.7066	2.0383	5.2002
COLO 800	GDSC2	4.5513	6.7228	2.5038	2.5118
SK-MEL-31	GDSC2	4.5515	9.2427	1.3132	9.4446
CHL-1	GDSC2	4.6096	6.8922	2.4614	2.6505
SK-MEL-5	GDSC2	4.6166	6.2445	2.7465	1.1942
SK-MEL-24	GDSC2	4.6308	7.7897	2.0619	4.8731
SK-MEL-2	GDSC2	4.6634	5.6254	3.0084	0.2005
CP66-MEL	GDSC2	4.7523	10.4715	0.8577	11.5763
G-361	GDSC2	4.8556	8.3234	1.9545	5.0721
GAK	GDSC2	4.8903	6.3374	2.8357	0.5842
SK-MEL-1	GDSC2	4.9022	6.2823	2.8617	0.4896
WM1552C	GDSC2	4.9312	7.2556	2.479	2.0971
LB373-MEL-D	GDSC2	4.9313	6.5607	2.7667	0.8044
DJM-1	GDSC2	5.022	12.6231	0.0008	15.3991
CP50-MEL-B	GDSC2	5.0323	6.8539	2.6962	0.9951
WM115	GDSC2	5.1702	6.5217	2.8805	0.2985
HMV-II	GDSC2	5.2141	14.7446	-0.8994	18.9637
A-388	GDSC2	5.2536	7.3044	2.6178	1.1135
COLO 679	GDSC2	5.279	6.8909	2.7884	0.494
LB2518-MEL	GDSC2	5.287	6.6995	2.8614	0.2966
MMAc-SF	GDSC2	5.2919	7.9184	2.3835	2.1107
WM35	GDSC2	5.3671	7.4843	2.598	1.0937
A-431	GDSC2	5.4216	7.3421	2.6774	0.76
WT2-iPS	GDSC2	5.4921	7.082	2.8026	0.3531
UACC-257	GDSC2	5.5057	6.6368	2.9614	0.0737
IST-MEL1	GDSC2	5.5116	7.8463	2.5199	1.278
EquiPSC Line K2	GDSC2	4.434	8.8511	1.4204	9.0838

Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
HuTu 80	GDSC2	4.0617	11.4623	-0.1494	18.5407

Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Soft Tissue Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SW982	GDSC2	3.8996	8.9043	0.9964	12.9059
STS-0421	GDSC2	3.9102	6.2167	2.3307	4.7576
KYM-1	GDSC2	3.9521	5.7301	2.5939	3.0672
SK-UT-1	GDSC2	4.1062	6.4153	2.3699	4.0921
GCT	GDSC2	4.1095	6.2425	2.4543	3.5809
VA-ES-BJ	GDSC2	4.1502	6.391	2.4106	3.7591
SW684	GDSC2	4.226	7.7514	1.8079	7.2367
TE 441.T	GDSC2	4.2593	10.1374	0.6604	13.8627
MES-SA	GDSC2	4.2762	5.7535	2.7791	1.4615
Hs 633.T	GDSC2	4.3136	5.9255	2.7242	1.6944
G-402	GDSC2	4.3533	8.3025	1.63	8.02
EW-8	GDSC2	4.3836	6.2437	2.6223	2.1322
G-401	GDSC2	4.5122	8.0759	1.8487	6.365
A-204	GDSC2	4.5516	7.6058	2.0976	4.8164
Rh41	GDSC2	4.6654	12.3675	-0.1359	16.914
MFH-ino	GDSC2	4.8827	8.8225	1.7382	6.2646
SW872	GDSC2	4.8916	6.798	2.6522	1.3207
HT-1080	GDSC2	5.0379	6.6461	2.7803	0.6726
RKN	GDSC2	5.099	6.4618	2.8746	0.345
Rh30	GDSC2	5.2101	7.1613	2.6549	1.0042
RD	GDSC2	5.2153	11.0939	0.8781	10.4396
SK-LMS-1	GDSC2	6.0721	7.7628	2.7779	0.2135

Cancer Drug Sensitivity Data Curated from 29 Cell Line(s) in Stomach Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
ECC10	GDSC2	2.6195	19.1816	-5.2006	36.6216
SNU-16	GDSC2	3.2858	5.1993	2.353	6.2407
HSC-39	GDSC2	3.3577	5.425	2.3001	6.3662
Fu97	GDSC2	3.4389	6.0731	2.0426	7.7636
NUGC-4	GDSC2	3.662	8.4771	1.022	13.4043
Hs 746.T	GDSC2	3.7266	5.4506	2.5731	3.6864
MKN1	GDSC2	3.8535	6.9001	1.9542	7.2242
ECC12	GDSC2	3.8841	5.3063	2.75	2.2757
MKN45	GDSC2	3.9486	6.766	2.0901	6.1517
KATO III	GDSC2	3.9883	8.118	1.4541	9.9591
MKN28	GDSC2	4.006	6.9312	2.0507	6.2598
AGS	GDSC2	4.1792	6.9816	2.1478	5.2772
23132/87	GDSC2	4.2127	9.6969	0.8429	12.9672
IM95	GDSC2	4.216	6.6402	2.3357	4.0729
SK-GT-2	GDSC2	4.3382	6.4578	2.4982	2.8957
NCI-N87	GDSC2	4.3385	10.0709	0.7527	13.1538
MKN7	GDSC2	4.3819	6.1782	2.6505	1.9834
HGC-27	GDSC2	4.6508	7.2212	2.3369	3.2683
SNU-1	GDSC2	4.6897	6.7697	2.5603	2.011
TMK-1	GDSC2	4.7491	8.2598	1.9169	5.4888
NUGC-3	GDSC2	4.76	7.9392	2.0733	4.5671
GCIY	GDSC2	4.9178	7.8409	2.2131	3.5141
OCUM-1	GDSC2	4.9734	8.1541	2.104	4.0234
SCH	GDSC2	4.9951	6.4666	2.8308	0.531
RERF-GC-1B	GDSC2	5.1624	7.6662	2.4241	2.0736
RF-48	GDSC2	5.2005	6.9263	2.7424	0.6899
SNU-5	GDSC2	5.2174	6.4552	2.9218	0.1921
TGBC11TKB	GDSC2	5.589	7.5566	2.6663	0.6876
SNG-M	GDSC2	5.1848	7.301	2.5872	1.3047

Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Thyroid Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
CAL-62	GDSC2	3.7163	9.539	0.5356	15.9995
KMH-2	GDSC2	3.8804	6.445	2.1979	5.6469
IHH-4	GDSC2	3.9659	7.0632	1.957	6.9324
8305C	GDSC2	4.1954	11.5498	-0.0887	17.8917
8505C	GDSC2	4.2073	6.6762	2.3128	4.2261
TT2609-C02	GDSC2	4.2277	6.5878	2.3681	3.8573
K5	GDSC2	4.2674	7.6701	1.8765	6.7278
HTC-C3	GDSC2	4.3175	6.3567	2.5321	2.7404
B-CPAP	GDSC2	4.4392	6.2247	2.6619	1.8382
FTC-133	GDSC2	4.5528	6.7224	2.5049	2.5038
ML-1 [Human leukemia]	GDSC2	4.6565	6.5838	2.6231	1.7386
TT	GDSC2	4.7604	10.5034	0.848	11.6116
WRO	GDSC2	4.9333	7.593	2.3327	2.8468
BHT-101	GDSC2	5.1424	6.9402	2.7117	0.8426
ASH-3	GDSC2	5.1767	6.6384	2.8407	0.3987
CGTH-W-1	GDSC2	5.2699	6.7227	2.8465	0.3397

Cancer Drug Sensitivity Data Curated from 40 Cell Line(s) in Upper Aerodigestive Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
SAS	GDSC2	3.4722	6.1584	2.0269	7.77
HO-1-u-1	GDSC2	3.5405	5.6263	2.3465	5.5689
KOSC-2	GDSC2	3.6714	6.1168	2.204	6.1238
BB49-HNC	GDSC2	3.7431	10.2371	0.2088	17.6498
BICR 78	GDSC2	3.8692	8.0639	1.3902	10.6517
Detroit 562	GDSC2	3.8915	5.9133	2.4647	3.9781
BB30-HNC	GDSC2	3.9123	6.1894	2.3454	4.6625
PCI-04B	GDSC2	3.942	6.5695	2.1814	5.6039
HSC-3	GDSC2	4.0205	10.4143	0.3398	16.2071
HO-1-N-1	GDSC2	4.1762	6.1668	2.5328	2.9902
DOK	GDSC2	4.1882	7.3676	1.9676	6.3517
KON	GDSC2	4.2328	7.3666	1.9992	6.0609
SAT [Human HNSCC]	GDSC2	4.2568	7.054	2.1657	5.0047
JHU-011	GDSC2	4.2944	8.0302	1.7208	7.6078
JHU-029	GDSC2	4.2969	6.9484	2.2426	4.4632
HSC-4	GDSC2	4.4121	6.415	2.5618	2.4167
BICR 31	GDSC2	4.4191	6.8419	2.3706	3.4805
SCC-9	GDSC2	4.4212	8.5064	1.5789	8.1718
PCI-06A	GDSC2	4.5471	8.6692	1.5876	7.8403
NCI-H3118	GDSC2	4.5541	6.9599	2.3983	3.0881
SCC-4	GDSC2	4.6381	7.9735	1.9803	5.3345
Ca9-22	GDSC2	4.6396	7.4363	2.2316	3.88
HSC-2	GDSC2	4.6944	7.7197	2.1344	4.3368
OSC-19	GDSC2	4.7501	11.4914	0.3577	14.2594
BICR 22	GDSC2	4.776	10.6243	0.8001	11.8392
PE/CA-PJ15	GDSC2	4.8048	6.4556	2.7507	0.9809
BICR 10	GDSC2	4.8432	6.7423	2.6515	1.3768
PCI-15A	GDSC2	4.8616	6.6865	2.6836	1.2128
LB771-HNC	GDSC2	4.9033	8.3281	1.9819	4.8294
UPCI-SCC-090	GDSC2	5.243	7.9257	2.3552	2.3079
SKN-3	GDSC2	5.3288	7.11	2.7266	0.6571
JHU-022	GDSC2	5.4133	11.9313	0.6108	11.446
CAL-27	GDSC2	5.5452	6.964	2.8641	0.2039
OSC-20	GDSC2	5.6534	8.1425	2.4666	1.3661
BHY	GDSC2	5.7034	7.5849	2.7023	0.5166
SCC-25	GDSC2	5.7177	7.8976	2.5909	0.8524
CAL-33	GDSC2	5.8613	7.5539	2.7738	0.281
SCC-15	GDSC2	5.9233	7.7868	2.7146	0.3872
FaDu	GDSC2	6.1761	12.7984	0.6986	9.4872
PCI-30	GDSC2	6.1953	14.8775	-0.2722	14.1235

Cancer Drug Sensitivity Data Curated from 16 Cell Line(s) in Urinary Tract Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
KU-19-19	GDSC2	3.4134	7.3444	1.3864	11.9261
BFTC-905	GDSC2	3.572	5.7809	2.2942	5.8151
639V	GDSC2	3.8108	8.9886	0.885	13.7874
SW1710	GDSC2	4.2736	7.1306	2.1404	5.1214
RT-4	GDSC2	4.4443	9.0149	1.3479	9.4876
SW780	GDSC2	4.6526	7.2746	2.3136	3.395
HT-1376	GDSC2	4.6972	9.4391	1.3198	9.0796
CAL-29	GDSC2	5.314	6.7516	2.853	0.3053
UM-UC-3	GDSC2	5.318	6.9979	2.7644	0.5439
647V	GDSC2	5.3422	7.1352	2.7227	0.6612
T24	GDSC2	5.3993	7.3914	2.6488	0.8765
HT-1197	GDSC2	5.5466	7.5044	2.6683	0.7077
TCCSUP	GDSC2	5.6927	7.2834	2.8066	0.2697
RT-112	GDSC2	6.0837	7.2707	2.9458	0.0326
J82	GDSC2	6.2931	7.9491	2.7923	0.1453
5637	GDSC2	6.3333	8.2268	2.7116	0.2587

Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue

Cell Line	Original Dataset	IC50	IC90	EC50	AUC
TC-YIK	GDSC2	2.452	5.5473	1.4213	14.8051
BPH-1	GDSC2	2.8614	5.4958	1.8308	10.8671
NCC-IT	GDSC2	3.6424	5.5754	2.4499	4.6566
HeLa	GDSC2	3.654	5.3601	2.5646	3.9118
DSH1	GDSC2	3.6547	6.6439	1.9294	7.8884
CAL-39	GDSC2	3.6921	5.6949	2.428	4.6701
KGN	GDSC2	3.7069	8.6167	0.9881	13.4772
JAR	GDSC2	3.8298	5.6342	2.5568	3.5517
MS751	GDSC2	3.8744	7.3179	1.7636	8.3529
PA-1	GDSC2	3.8781	5.9446	2.4402	4.158
NT2-D1	GDSC2	3.9203	6.0708	2.4086	4.257
OVCA420	GDSC2	3.9479	5.7297	2.5912	3.0917
LB831-BLC	GDSC2	4.0053	7.5136	1.7648	8.021
SKG-IIIa	GDSC2	4.1314	6.9387	2.1356	5.4557
SW954	GDSC2	4.2433	6.6561	2.346	3.9573
SKN	GDSC2	4.2755	10.8142	0.3378	15.5448
Ca Ski	GDSC2	4.2966	8.4837	1.5014	8.922
JHOS-3	GDSC2	4.4688	7.1024	2.2806	3.9086
C-33 A	GDSC2	4.5958	9.9147	1.0174	11.0451
PEO1	GDSC2	4.6381	7.2343	2.3234	3.365
UWB1.289	GDSC2	4.7198	7.6346	2.1893	3.9788
JEG-3	GDSC2	4.8375	7.0875	2.5017	2.1076
OVMIU	GDSC2	4.8837	7.5387	2.3289	2.9414
ACC-OV7	GDSC2	4.9298	12.0323	0.2232	14.5182
HT-3	GDSC2	5.244	7.5622	2.5086	1.5872
SiHa	GDSC2	5.3616	6.6154	2.9184	0.1584
OVCA433	GDSC2	5.3617	7.7147	2.5028	1.4911
SW756	GDSC2	5.3997	6.791	2.8712	0.2344
SiSo	GDSC2	5.4134	7.7085	2.5297	1.3275
HEC-1	GDSC2	5.4366	7.1623	2.7514	0.5163
HEY	GDSC2	5.5093	8.0691	2.4285	1.6638
C-4-I	GDSC2	5.5471	7.2905	2.7483	0.4681
ME-180	GDSC2	5.5604	10.8135	1.2368	7.7912
OV17R	GDSC2	5.5638	11.1791	1.0676	8.7046
DoTc2 4510	GDSC2	5.6635	7.689	2.6473	0.7022
NEC8	GDSC2	5.6778	7.1916	2.8332	0.2226
OMC-1 [Human cervical carcinoma]	GDSC2	5.7455	7.5275	2.7396	0.4
SW962	GDSC2	6.0282	7.8251	2.7403	0.2945
PWR-1E	GDSC2	6.0302	7.5595	2.8324	0.1412

References

• [1] Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition. J Med Chem. 2016 Feb 25;59(4):1425-39.